My cousin has a ball obsessed dog. He stayed with us for 5 weeks. It wasn't long enough to work on and resolve his issue but we were going through the following process:
We removed the ball from his life entirely because it was causing a great deal of stress. I mean excited stress that you are talking about not anxiety or fear stress. Eg heavy shallow panting, whining, pacing, barking, jumping, dilated pupils.
We then began working on his obedience - heeling was a main focus point.
Once he was able to do this, we were introducing the ball but not using it. We need to change the thought process when the ball is presented. Like you would for a dog that gets excited over seeing a lead (lead means going for a walk = jump around like a lunatic).
Once you change the thought process about the ball, you can then consider using it as a reward for certain tasks, like obedience or learning new skills.
As soon as his mind changes back to stress you need to put the ball away and go back a few steps. Teach the dog how to play and enjoy a ball while relaxed. Playing with such intensity with adrenalin running through the body is just as unhealthy as fear related stress and anxiety.
I hope that made sense...