From a person to person perspective I think breeding is fine so long as you sell the pups and do all the legal work (each state has different laws).
From a breeding perspective im obviously into greyhound and I can tell you that from what I know and IMHO racing greyhounds are by far the fittest, healthiest and most well bred robust canine there is purely because of the way they are bred and the reasons for it.
Make sure the male and female compliment each others strengths and weaknesses. Look into their blood lines if possible and make sure there is no close relationship and no major health issues and you should be right. Good luck.