They do poo a rediculous amount. When we first got the domestic mice, I handled them quite a lot then I got sick of them pooing every 10 seconds lol....I did want to feed them to the snake Winston, but unfortunately we put him out on the clothes line for a slither, and forgot about him when the boyfriend's mate called, and when we remembered when we got home from being out, Winston was gone..I was quite sad as I was just starting to handle him as well.