Well I know a lot of people who breed and so far the only ones that I have seen have any problems (except of course for the stories posted on these forums) are those with purebreeds. I am not anti-cross breed, but I do believe you need to have a purpose and conduct both health and temperament/work ability tests before breeding any dogs. But recently one of the ladies I work with has started breeding her Kelpie. Now this is a dog that she rescued somehow undesexed, and since decided to breed it to a friends' labrador cross. There have been no issues, her kelpie conceived easily, gave birth naturally at home to 7 puppies, raised them all without help and all puppies survived and seemed healthy. She sold them all for a good price and even had people fighting over the puppies (she received lots of calls and emails daily from people wanting one). She was somewhat choosey about the homes, made sure the people were told that Kelpies are an active dog but then, let the pups go at 6-7 weeks because they were becoming a handful and expensive to feed.
The outcome? She has made a large profit and feels good about what she has done - the puppies do seem to have gone to good homes. Now she is considering doing it again just because they have so many other people still wanting puppies. I don't even know what to say. The truth is for most people breeding two healthy crossbreed dogs, the pups will be healthy and the process won't require vet intervention - I see it all the time. When the person has homes lined up and is making a fair profit from having litters with her well-loved family dog (so not a puppy mill or anything) well where do you even begin?